Powered by AlphaFold, RFdiffusion & ESM2

Protein Design Reimagined

The complete platform for computational protein design. Predict structures, refine models with machine learning, and translate your research to the wet lab — all in one place.

200M+
Protein Structures
14+
Design Methods
220K+
Database Entries
5+
Analysis Tools
Platform Features

Everything You Need for Protein Research

From structure prediction to wet lab translation — ProteinLab provides a complete computational biology workflow in a single, integrated platform.

Interactive 3D Viewer

Visualize protein structures in real-time with NGL Viewer. Rotate, zoom, and analyze with multiple representation modes.

AlphaFold & PDB Integration

Direct access to 200M+ AlphaFold predicted structures and the RCSB Protein Data Bank with 220K+ experimental entries.

ML-Powered Refinement

Apply state-of-the-art ML methods including RFdiffusion, BindCraft, ESM2, and BoltzGen for structure optimization.

Bioinformatics Analysis

Run sequence alignment, motif detection, stability prediction, and binding site identification powered by AI.

Collaboration Tools

Share protein models with team members, manage access permissions, and collaborate on research projects.

Export & Integration

Export structures in PDB and mmCIF formats, download analysis reports, and integrate with wet lab workflows.

ML Design Methods

14+ State-of-the-Art Design Methods

Access the latest machine learning models for protein design, from diffusion-based backbone generation to language model-guided sequence optimization. Each method is benchmarked and ready to apply to your research targets.

Diffusion models for de novo backbone generation
Protein language models for sequence optimization
Binder design with high affinity and specificity
Reinforcement learning for enzyme engineering
RFdiffusion
Diffusion
1.5K+generated
BindCraft
Binder Design
594generated
AlphaFold 3
Structure Prediction
500K+generated
ESM2
Language Model
38generated
BoltzGen
Diffusion
1.7K+generated
EvoDiff
Diffusion
26generated
Research Workflow

From Sequence to Lab in 4 Steps

01

Input Structure

Enter a PDB ID, UniProt accession, FASTA sequence, or upload your own structure file.

02

Visualize & Analyze

Explore the 3D structure interactively. Run bioinformatics analyses to understand function.

03

Refine with ML

Apply machine learning methods to optimize stability, binding affinity, and structural quality.

04

Export & Collaborate

Download PDB/mmCIF files, share with collaborators, and translate findings to wet lab.

Start for Free

Ready to Accelerate Your Protein Research?

Join researchers worldwide using ProteinLab to design, analyze, and optimize protein structures with cutting-edge machine learning.